Chemistry

Operators, Schrodinger Equation, one dimensional problems, harmonic oscillator, angular momentum, hydrogen atom, scattering theory. One year (two semesters) Undergraduate Physical Chemistry or equivalent.

Statistical methods, statistical thermodynamics, Ensembles, Partition functions. Quantum statistics. Kinetic theory of transport processes. One year (two semesters) of Undergraduate level Physical Chemistry or equivalent.

Spectroscopic methods for the structural determination of molecular systems, including: NMR (1D and 2D), mass spectrometry, infrared and ultraviolet-visible spectroscopies.

An expanded presentation of fundamental topics in organic chemistry: structure, bonding, stereochemistry, molecular orbital theory, reactive intermediates and reaction mechanisms.

An intensive survey of the basic principles of inorganic chemistry from the viewpoints of bonding, structure, and energetics. Topics include periodicity, symmetry, kinetics and mechanisms,spectroscopy, and acid- base theory. student who expects to do research in inorganic chemistry.

A discussion of the fundamentals of quantum mechanics, statistical mechanics, and classical thermodynamics with applications to small molecules, solid state and polymers.

Apply key concepts in chemistry to global scales by examining chemical systems within Earth's lithosphere, hydrosphere and atmosphere. Examine and discuss natural processes as well as anthropogenic impacts like climate change and environmental contamination using central scientific literature.

An intensive survey of selected principles and techniques in modern analytical chemistry. Topics may include basic statistics, sampling, complexation and extraction, equilibria, molecular and atomic spectroscopy, microscopy, electroanalysis, and chromatography.

Protein structure; protein function and structure-function relationships in proteins; regulatory mechanisms in proteins, including ligand effectors, covalent modification, and proteolysis; structural and functional genomics and proteomics.

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M.S. thesis research to be conducted in partial fulfillment of the M.S. degree in chemistry by those students who choose the thesis option. The research will be directed by a faculty member. Prerequisites: M.S. research I, II, and III.

Presentation of M.S. thesis research, literature presentations by students, and faculty research seminars.

Survey of organic reactions with emphasis on modern synthetic methods and their applications to the synthesis of complex organic compounds. Enolates, carbonyl condensation reactions, functional group interconversions, electrophilic addition reactions, reductions, organometallic reagents, concerted reactions, oxidations Synthetic strategies including retrosynthetic analysis in the context of specific examples of multi-step synthesis from recent literature.

Emphasis on novel inorganic materials. Topics may include: solid state catalysis, semi- and superconductors, ceramics, batteries and energy sources.

A survey of principles and applications of methods such as nuclear magnetic resonance, vibrational and electronic spectroscopies, electron microscopies, scanning probe microscopies, and electrochemistry.

Examination of the bonding, spectroscopic properties and reactivity of a range of ligands and complexes. Reaction mechanisms and catalytic cycles will be emphasized.

Topics include: step- and chain- polymerizations, copolymerizations, molecular weight determination, polymer morphology, polymer testing and chacterization, and current advances in polymer chemistry.

The roles metal ions play in biological systems are explored using relevant examples from natural systems and areas of current research including (but not limited to): catalysis, photosynthesis, respiration, biomimetic modeling, and solar energy conversion.

Provides basis for theory and applications of X-ray crystallography. Topics include properties of crystals and x-rays, lattice symmetry, geometry of diffraction, calculations of diffracted intensities and amplitutes, Fourier series method, rotation method and Laue method.

A study of the relationship between protein structure and disease, enzymes as therapeutic targets, peptide hormones and obesity, and glucose metabolism and cancer.

The course provides a survey of recent microscopy advances that push the boundaries of image resolution. Instruments and techniques that probe the inner workings of the cell at the level of individual molecules will be discussed, including confocal, TIRF, quantum dots, AFM, and PALM.

Physical principles and applications of NMR to compounds of interest to chemists and biochemists. Solution and solid state NMR, 2D-NMR, advance techniques and real laboratory problems will be covered.

Brief overview of parasitology, the unique biochemistry associated with parasites, discussions of relevant therapeutic applications. The parasites responsible for malaria, toxoplasmosis, trichomoniasis, giardiasis, and African Sleeping Sickness will be studied. The biochemistry of host parasite interaction will also be explored.

Structural and mechanistic aspects of enzymes. Topics include chemical catalysis, steady state and pre-steady state kinetics, mechanisms, and biological relevance of specific enzyme systems.

Elective course for students seeking work experience in chemical industry. Departmental approval required for a specific work opportunity. Prerequisite: Completion of 30 graduate credits.

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Approaches to drug discovery: modification of natural products, synthesis, screening, and rational design. Recent and historical examples of therapeutically significant pharmaceuticals will be emphasized.

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The physical chemistry of solutions, surfaces, monolayers, surfactants, emulsions, colloids, and interfaces.

Provides basis for theory and applications of X-ray crystallography. Topics include properties of crystals and X-rays, lattice symmetry, geometry of diffraction, calculations of diffracted intensities and amplitudes, Fourier series method, rotation method, and Laue method.

Focus on basic theories behind popular computational models (e.g., molecular mechanics, density functional theory) and their application to chemical problems.

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Through this course, students will achieve an advanced understanding of electrochemical concepts and techniques. This course will delve into topics related to electrochemical cell processes, electrode properties, kinetics and thermodynamics of electrochemical reactions, and electroanalytical techniques used in chemical analysis.

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This course will focus on the physical tools that exist to obtain information about biological macromolecules, with an emphasis on spectroscopic and imaging techiniques (e.g., circular dichroism, fluorescence spectroscopy, FRET, electron microscopy, atomic force microscopy, dynamic light scattering, analytical ultracentrifugation, x-ray crystallography, and surface plasmon resonance). Undergraduate students approved to take CHM-9661 require the prerequisite of CHM 4621 or CHM 4610 or CHM 4611. Undergraduates must have permissions to enroll in the graduate course from the Department.

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Principles, techniques and applications for the large-scale study of proteins, particularly in human. Mass spectrometry will be covered in detail, and alternative methods and approaches will also be covered.

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